A079049 Recaman variation: a(1) = 1; for n > 1, a(n) = a(n-1)-prime(n) if that number is positive and not already in the sequence, otherwise a(n) = a(n-1)+prime(n).

1, 4, 9, 2, 13, 26, 43, 24, 47, 18, 49, 12, 53, 10, 57, 110, 51, 112, 45, 116, 189, 268, 185, 96, 193, 92, 195, 88, 197, 84, 211, 80, 217, 78, 227, 76, 233, 70, 237, 64, 243, 62, 253, 60, 257, 58, 269, 46, 273, 44, 277, 38, 279, 28, 285, 22, 291, 20, 297, 16, 299, 6, 313